Annette von Drygalski Selected Research

Factor Va

1/2022	An engineered activated factor V for the prevention and treatment of acute traumatic coagulopathy and bleeding in mice.
11/2020	An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms.
1/2014	An engineered factor Va prevents bleeding induced by anticoagulant wt activated protein C.

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Annette von Drygalski Research Topics

Disease

18	Hemorrhage 01/2022 - 04/2013
12	Hemophilia A (Haemophilia) 11/2022 - 07/2013
8	Joint Diseases (Joint Disease) 11/2021 - 11/2015
5	Inflammation (Inflammations) 11/2021 - 04/2009
4	Vascular Remodeling 01/2021 - 01/2016
4	Anemia 03/2020 - 04/2009
3	Iron Deficiencies 03/2011 - 10/2008
2	Hemarthrosis 01/2021 - 11/2019
2	Weight Loss (Weight Reduction) 04/2013 - 03/2011
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2022
1	Hypertension (High Blood Pressure) 11/2022
1	HIV Infections (HIV Infection) 11/2022
1	Hemophilia B (Haemophilia B) 11/2021
1	Cysts 11/2021
1	Arthritis (Polyarthritis) 11/2021
1	Synovitis 11/2021
1	Bone Cysts (Bone Cyst) 11/2021
1	AIDS-Related Complex (ARC) 09/2021
1	Atrial Fibrillation 01/2021
1	COVID-19 01/2021
1	Stroke (Strokes) 01/2021
1	Osteoarthritis 09/2019
1	Liver Diseases (Liver Disease) 11/2017
1	Epidural Abscess 03/2016
1	Hepatitis C 01/2016
1	Lacerations 01/2014
1	Endotoxemia 04/2013
1	Albuminuria 04/2013
1	Fatigue 09/2011
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 04/2009
1	Morbid Obesity 04/2009
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 04/2009

Drug/Important Bio-Agent (IBA)

8	Factor VIII (Coagulation Factor VIII)IBA 12/2021 - 01/2018
7	IronIBA 11/2021 - 10/2008
5	Blood Coagulation Factors (Coagulation Factor)IBA 11/2022 - 11/2015
3	Factor VaIBA 01/2022 - 01/2014
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2016
2	DisulfidesIBA 01/2022 - 11/2020
2	HemosiderinIBA 11/2021 - 12/2020
2	Protein CIBA 11/2020 - 01/2014
2	Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA 10/2019 - 10/2018
2	Ferritins (Ferritin)IBA 03/2011 - 04/2009
1	Neutralizing AntibodiesIBA 11/2022
1	Antihypertensive Agents (Antihypertensives)IBA 11/2022
1	Factor IX (Coagulation Factor IX)FDA LinkGeneric 11/2021
1	BAX 335IBA 11/2021
1	Collagen Type VIIIIBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	emicizumabIBA 01/2021
1	Pain-FreeIBA 01/2021
1	CollagenIBA 01/2021
1	Complement C4 (Complement Component 4)IBA 01/2021
1	AutoantibodiesIBA 01/2021
1	Collagen Type IV (Type IV Collagen)IBA 01/2021
1	Factor Xa InhibitorsIBA 11/2020
1	apixabanIBA 11/2020
1	FIIaIBA 11/2020
1	Dabigatran FDA Link 11/2020
1	RivaroxabanIBA 11/2020
1	Hemoglobins (Hemoglobin)IBA 03/2020
1	PlasminogenIBA 10/2019
1	3'-(1-butylphosphoryl)adenosineIBA 12/2018
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 10/2018
1	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2018
1	Prothrombin (Factor II)IBA 11/2017
1	Vitamin K FDA Link 11/2017
1	Factor VIIa (Activated Factor VII)IBA 03/2016
1	A-factor (Streptomyces)IBA 03/2016
1	Thrombin FDA Link 03/2016
1	CholesterolIBA 01/2016
1	Therapeutic UsesIBA 01/2014
1	AnticoagulantsIBA 01/2014
1	AntibodiesIBA 07/2013
1	LipopolysaccharidesIBA 04/2013
1	Endothelial Protein C ReceptorIBA 04/2013
1	Evans Blue (Blue, Evans)FDA Link 04/2013
1	ZincIBA 04/2009
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 04/2009
1	MicronutrientsIBA 04/2009
1	Folic Acid (Vitamin M)FDA LinkGeneric 04/2009
1	CopperIBA 04/2009
1	VitaminsIBA 04/2009

Therapy/Procedure

4	Therapeutics 11/2021 - 01/2014
2	Bariatric Surgery 03/2011 - 04/2009
1	Tissue Expansion 09/2021
1	Craniotomy 03/2016
1	Liver Transplantation 01/2016
1	Surgical Instruments (Clip) 01/2014